About ORIvEDA's REISHI PRIMO
There is no Reishi supplement with better specifications available. Click here to see our authorised 'Supplement Facts' label, based on objective lab test reports.
ORIvEDA guarantees the presence of the main bioactive compounds and their bioavailability. Click here to see the most recent third party test results.
What sets Reishi mushrooms apart from pharmaceuticals and what makes them particularly effective is the synergistic effect of the combined bioactives (mainly Beta-Glucans, glycoproteins/proteo-glycans, polyphenols and triterpenes). Extraction defines the therapeutic potency, since we cannot digest non-extracted mushrooms properly. See this -highly recommended!- link for the details about this.
Extraction is essential for an actual therapeutic effect, and dual extraction is often the best option - it will make both water-solubles and insolubles bioavailable. Research found that the immunological effects of mushroom extracts are up to 10 times higher when compared against non-extracted powders.
In case you are interested in how ORIVeDA did its due diligence when developing Reishi Primo read this article, with a lot of objective background information about cultivation, extraction and other Reishi supplements.
Taking into account that a 2017 report concluded almost all Reishi sold in the US is not actually Reishi and lacks quality it's worthwhile reading material.
Hot water extracts (incl. home made Reishi tea), tinctures and powdered products at best contain only low concentrations of bioactives (which is why you never see them specified on the label of such products - it's better to keep it vague from a vendor's perspective). The bioavailability is always a major problem - if we can't digest all that good stuff we can't benefit from it, right?
Reishi Primo is one of the very few Reishi products that actually offers all those bioactives in a bioavailable form, guaranteeing not only the presence but also the quantity of those compounds. Odd as it may seem, it is actually rare to find Reishi with clear specifications, let alone verifiable specifications. ORIvEDA's mantra is and always will be: quality claims should be supported by third party test reports to be reliable and trustworthy.
Reishi Primo is produced using a multi-step extraction procedure (hot water, alcohol, alcohol precipitation) which ensures a high purity product, as opposed to extraction using only hot water or a mix of water and alcohol in a single-step extraction process.
For an extensive background about Reishi, please read this article.
Science has been researching mushrooms for decades. Below we've listed the main targets in Reishi research.
Side effects and safety
Some people taking high dosages of 1.5 - 9 grams per day reported one or more of the following side effects: temporary sleepiness, thirst, rashes, bloating, frequent urination and diarrhea. Taking the extract together with vitamin C seemed to improve many of the side effects. Lowering the dosage also helped.
These reports do not give details about the quality and properties of the extracts that were consumed; and taking into account the poor quality level of most Reishi products (see this 2017 report) it is not unlikely that at least some of these side effects might be related to that, so this appears not to be a direct cause for alarm.
As said, the anti-microbial combination of Reishi with four commonly used antibiotics resulted in an additive or synergistic effect in most, but not all, instances. Reishi appears to cause cefazolin and ampicillin to be less effective against Proteus vulgaris (known to cause urinary tract infections and wound infections).
Reishi extracts rich in triterpenes are very powerful; these might not be the best choice for everybody.
Reishi with a high level of triterpenes should not be used in hormone-related breast cancers - there are contradicting results, so it is best to stay on the safe side. The anti-androgenic effects of Reishi can suppress libido.
Because Reishi has immune-balancing properties, it should not be used together with immune-suppressants, like those prescribed after a transplant. The blood sugar lowering effects can cause fatigue in those that are highly susceptible. In general these people are also very susceptible to e.g. caffeine and alcohol, or are diabetic. Taking the extract together with a sugar-containing liquid can neutralise this effect.
Rare side effects are: not sleeping well, bad, vivid dreams, feelings of anxiety, feeling mentally numb/clouded or having a sense of heightened mental activity. These effects are most likely caused by a genetic anomaly, like overreacting to specific triterpenes, such as lanostan. Just like with Cordyceps some people experience effects that are exactly the opposite of what usually happens. This is personal and due to genetic wiring.
Lanostan triggers the function of the adrenal glands, which are responsible for adrenaline/nor-adrenaline production. If you’re very sensitive to this you can experience hyper-activity which can make you feel anxious, etc. If you experience daily stress on top of that, this will also push the production of adrenaline/noradrenaline in your body, potentially causing anxiety.
Reishi Primo contains a relatively high level of triterpenes; if you experience these side effects it might be better to look for a different mushroom extract or to choose a hot-water-extracted-only Reishi extract, which contains no triterpenes.
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